{"id":3171,"date":"2020-07-20T18:37:46","date_gmt":"2020-07-20T18:37:46","guid":{"rendered":"https:\/\/daslab-tmp.su.domains\/?p=3171"},"modified":"2024-08-01T18:45:54","modified_gmt":"2024-08-01T18:45:54","slug":"weve-resolved-the-sars-cov-2-frameshift-stimulation-element-with-our-hybrid-structure-determination-pipeline-ribosolve-and-we-report-effects-of-antisense-oligonucleotides-on-this-rnas-function-an","status":"publish","type":"post","link":"https:\/\/daslab-tmp.su.domains\/?p=3171","title":{"rendered":"We&#8217;ve resolved the SARS-CoV-2 frameshift stimulation element with our hybrid structure determination pipeline Ribosolve, and we report effects of antisense oligonucleotides on this RNA&#8217;s function and on virus replication in cell culture. Read more in our bioRxiv preprint. Many thanks to our colleagues in Glenn, Chiu, d&#8217;Souza, and Baric labs and SLAC for this fruitful collaboration, much of which occurred in the midst of.our university shutdowns."},"content":{"rendered":"<p>We&#8217;ve resolved the\u00a0<b>SARS-CoV-2 frameshift stimulation element\u00a0<\/b>with our hybrid structure determination pipeline Ribosolve, and we report effects of antisense oligonucleotides on this RNA&#8217;s function and on virus replication in cell culture. Read more in our\u00a0<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.07.18.209270v1\" target=\"_blank\" rel=\"noopener\">bioRxiv preprint<\/a>. Many thanks to our colleagues in Glenn, Chiu, d&#8217;Souza, and Baric labs and SLAC for this fruitful collaboration, much of which occurred in the midst of.our university shutdowns.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>We&#8217;ve resolved the\u00a0SARS-CoV-2 frameshift stimulation element\u00a0with our hybrid structure determination pipeline Ribosolve, and we report effects of antisense oligonucleotides on this RNA&#8217;s function and on virus replication in cell culture. Read more in our\u00a0bioRxiv preprint. Many thanks to our colleagues in Glenn, Chiu, d&#8217;Souza, and Baric labs and SLAC for this fruitful collaboration, much of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3205,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-3171","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/posts\/3171","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3171"}],"version-history":[{"count":0,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/posts\/3171\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/media\/3205"}],"wp:attachment":[{"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3171"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3171"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}