{"id":3174,"date":"2020-08-24T18:37:50","date_gmt":"2020-08-24T18:37:50","guid":{"rendered":"https:\/\/daslab-tmp.su.domains\/?p=3174"},"modified":"2024-08-01T18:47:51","modified_gmt":"2024-08-01T18:47:51","slug":"improving-the-stability-of-rna-vaccines-will-be-important-for-worldwide-vaccine-distribution","status":"publish","type":"post","link":"https:\/\/daslab-tmp.su.domains\/?p=3174","title":{"rendered":"Improving the stability of RNA vaccines will be important for worldwide vaccine distribution."},"content":{"rendered":"<p>Improving the stability of RNA vaccines will be important for worldwide vaccine distribution. We present a biophysical model for predicting RNA degradation in a new preprint led by\u00a0<b>Hannah Wayment-Steele<\/b>. Through a variety of mRNA design challenges launched through the\u00a0<b>OpenVaccine challenge<\/b>\u00a0on Eterna by\u00a0<b>Do Soon Kim<\/b>, we predict that the stability of any RNA vaccine can be increased at least two-fold either through rational design, as demonstrated by Eterna participants, or algorithmically, through the algorithms RiboTree (developed by\u00a0<b>Christian Choe<\/b>) and LinearDesign.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Improving the stability of RNA vaccines will be important for worldwide vaccine distribution. We present a biophysical model for predicting RNA degradation in a new preprint led by\u00a0Hannah Wayment-Steele. Through a variety of mRNA design challenges launched through the\u00a0OpenVaccine challenge\u00a0on Eterna by\u00a0Do Soon Kim, we predict that the stability of any RNA vaccine can be [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3202,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-3174","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/posts\/3174","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3174"}],"version-history":[{"count":0,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/posts\/3174\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=\/wp\/v2\/media\/3202"}],"wp:attachment":[{"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3174"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3174"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/daslab-tmp.su.domains\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3174"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}